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625-92-3 3,5-Dibromopyridine

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CAS： 625-92-3 MDL Number： MFCD00014634 MF： C5H3Br2N MW： 236.89 Purity： ≥98% Product Description： Relevant Medicine Name： - COA SDS

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Product InformationSafety InformationReferences

Flash point	84.3℃
Boiling point	222°C(lit.)
Density
Storage	Light sensitive

UN2811 6.1/PG3

With n-BuLi at -30 o, selective metallation occurs by exchange with one Br atom: J. Org. Chem., 16,1485 (1951). In contrast, using LDA in THF at -100 o, lithiation can be accomplished at the 4-position. Subsequent reaction with an electrophile can be followed by lithiation with n-BuLi to give 3-bromo-4,5-disubstituted pyridines: Tetrahedron Lett ., 37, 2565 (1996).