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2859-78-1 4-Bromoveratrole

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CAS： 2859-78-1 MDL Number： MFCD00008381 MF： C8H9BrO2 MW： 217.06 Purity： >97% Product Description： Relevant Medicine Name： - COA SDS

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Product InformationSafety InformationReferences

Flash point	109°C(lit.)
Boiling point	256°C(lit.)
Density	1.509g/mLat25°C(lit.)
Storage	Light sensitive

In the presence of sodamide, displacement by nucleophiles, e.g. anions of secondary amines or nitriles, occurs by an ortho-metallation-benzyne mechanism. The incoming nucleophile adds regioselectively such that the resulting anion is ortho-stabilized by methoxyl: J. Org. Chem., 48, 4397 (1983). The derived Grignard reagent has been used in the synthesis of the isoquinoline alkaloid (-)-mesembrine: J. Org. Chem., 60, 6785 (1995).