766-39-2 2,3-Dimethylmaleic Anhydride
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Does not undergo Diels-Alder reactions with furan, but does react with 1,3-Diphenyl-isobenzofuran, to give benzocantharadin: J. Org. Chem., 47, 4011 (1982). The use of the dimethylmaleoyl (DMM) group has been investigated for amino group protection in oligosaccharide synthesis. The DMM group is introduced using triethylamine as base. It promotes ? -linkage by neighboring group participation and is stable to acids and non-nucleophilic bases. Cleavage can be brought about by treatment with dilute aqueous NaOH: Eur. J. Org. Chem., 2305 (1998).
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