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6163-58-2 Tri(o-tolyl)phosphine

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 CAS:

6163-58-2

 MDL Number: MFCD00008514
 MF: C21H21P
 MW: 304.37
 Purity: ≥98%
 Product Description:
 Relevant Medicine Name: -
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Preferred phosphine ligand for use in combination with Pd salts in the Heck-type coupling reactions of vinylic halides. For examples, see Palladium(II)- acetate. For a review of the Heck reaction, see: Org. React., 27, 345 (1982).
The Pd-catalyzed amination of bromoarenes with 1-Boc-piperazine, in the presence of this ligand, provides a route to arylpiperazines of potential pharmacological interest: Tetrahedron Lett., 39, 2219 (1998).
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