16357-59-8 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline (EEDQ)
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Accela | SY003226 | bulk-g | POA | 0 | 31850 | 3-5 days | ![]() ![]() |
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Accela | SY003226 | 1000g | 164.00 | 0 | 2 | 3-5 days | ![]() ![]() |
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Reagent for peptide coupling. Reaction proceeds via the anhydride of the acid component: J. Am. Chem. Soc., 90, 823, 1651 (1968); Int. J. Pept. Prot. Res., 26, 493 (1985). For activation of ɑ -hydroxy acids, see: Tetrahedron Lett, 40, 3435 (1999) . Also used for the mild esterification of alcohols, e.g. for introduction of the levulinate protecting group: Tetrahedron Lett., 23, 2615 (1982). For a useful esterification technique applicable to primary, secondary and tertiary alcohols, see: J. Org. Chem., 60, 7072 (1995).
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