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20859-02-3 L-tert-Leucine

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 CAS:

20859-02-3

 MDL Number: MFCD00064218
 MF: C6H13NO2
 MW: 131.17
 Purity: ≥98%
 Product Description:
 Relevant Medicine Name: -
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ɑ-Amino acids have been used in combination with NaBH4 for the asymmetric reduction of ketones. Of a number of amino acids the sterically hindered tert-leucine was found to give the highest ee (95%) in the reduction of the carbonyl group of a 1,5-benzothiazepine intermediate in an efficient synthesis of the calcium antagonist diltiazem: J. Org. Chem., 61, 8586 (1996).
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