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16689-02-4 5-Nitro-2-thiophenecarbonitrile

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 CAS:

16689-02-4

 MDL Number: MFCD00052401
 MF: C5H2N2O2S
 MW: 154.15
 Purity: ≥98%
 Product Description:
 Relevant Medicine Name: -
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UN3439 6.1/PG3
Undergoes vicarious nucleophilic substitution at the 4-position; e.g. with chloromethyl phenyl sulfone and base, 5-nitro-4-(phenylsulfonylmethyl)thiophene-2-carbonitrile is formed in 91% yield: Tetrahedron, 51, 8339 (1995). For a review of vicarious nucleophilic substitution in heterocyclic compounds, see: Synthesis, 103 (1991).
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