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5331-43-1 Benzyl Carbazate

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 CAS:

5331-43-1

 MDL Number: MFCD00041890
 MF: C8H10N2O2
 MW: 166.18
 Purity: >97%
 Product Description:
 Relevant Medicine Name: -
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    Reagent for preparation of benzyloxycarbonyl (Z, Cbz) hydrazides of carboxylic acids, particularly N-protected amino acids. Subsequent hydrogenolysis gives the hydrazide which can be converted to the azide for coupling with a further amino acid residue by the azide method: J. Am. Chem. Soc., 74, 470 (1952); 87, 620 (1965);
    Has also been used in a similar manner for the preparation of simple acyl or sulfonyl hydrazides avoiding diacylation; the residual benzyl group is removable by hydrogenolysis: Synthesis, 244 (1980).
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