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20859-02-3 L-tert-Leucine

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CAS： 20859-02-3 MDL Number： MFCD00064218 MF： C6H13NO2 MW： 131.17 Purity： ≥98% Product Description： Relevant Medicine Name： - COA SDS

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ɑ-Amino acids have been used in combination with NaBH4 for the asymmetric reduction of ketones. Of a number of amino acids the sterically hindered tert-leucine was found to give the highest ee (95%) in the reduction of the carbonyl group of a 1,5-benzothiazepine intermediate in an efficient synthesis of the calcium antagonist diltiazem: J. Org. Chem., 61, 8586 (1996).